There are many signs and symptoms of testosterone deficiency in both men and women.


  • Muscle wasting
  • Abdominal weight gain
  • Fatigue
  • Depression
  • Irritability
  • Decreased libido
  • Erectile dysfunction
  • Loss of drive and ambition
  • Joint pains and stiffness


  • Muscle wasting
  • Weight gain
  • Fatigue
  • Dry, thin skin
  • Low self-esteem
  • Loss of libido
  • Decreased quality of orgasm
  • Bone loss
  • Sagging skin

There are many positive effects and health improvements from testosterone therapy including:


  • Improved energy
  • Better concentration
  • Less irritability and depression
  • Muscle building
  • Fat loss
  • Increased libido and sexual function
  • Improved sleep
  • Decreases risks for heart disease, Alzheimer’s, diabetes, and osteoporosis


  • Increased sense of well-being
  • Improved libido and sexual function
  • Increased muscle mass
  • Stronger bones
  • Better memory
  • More decisive and mentally sharper
  • Improved skin quality
  • Decreases risks for heart disease, diabetes, obesity, Alzheimer’s, and osteoporosis

Testosterone supplementation in women is very important to improve or reverse the above issues, but also is crucial in disease prevention.   Multiple scientific studies repeatedly show testosterone in women can help prevent heart disease, Alzheimer’s dementia, and osteoporosis.   Testosterone is safe and effective, while quite easy to use.  For most women, a simple once per day application of a testosterone cream raises blood levels to optimal ranges and safely bypasses the liver (oral testosterone or its derivatives is not safe to be taken orally for any reason).

Testosterone supplementation in men is more complex than for women.  The metabolism of testosterone to dihydrotestosterone (DHT) and estradiol`plays important roles in the safety and efficacy of testosterone restoration therapy (TRT).  In inexperienced hands, these metabolites can interfere with achieving the health benefits of TRT, while also may play a role in possible side effects.  There are four ways of taking testosterone: oral, transdermal, intramuscular, and pellet therapy.  Dr. Hammer almost exclusively prescribes once-weekly testosterone injections for his male patients.  This method has proven to be the most reliable, least expensive, safest, and easiest.   The injection is easily done by the patient himself or a loved one with minimal time and discomfort. 

A quick note on the other methods: 

  • Oral testosterone is toxic and never should be an option
  • Pellet therapy is in its infancy and has not panned out yet to be as convenient and efficacious as first thought
  • Transdermal testosterone often has inconsistent absorption patterns, can be messy, is dangerous by contact to young children and pregnant women, and very expensive


Properly done, TRT in both men and women has been repeatedly shown to be safe.  There is no scientific evidence that testosterone causes prostate cancer or heart disease.  To the contrary, there is overwhelming scientific evidence that testosterone protects against heart disease, diabetes, obesity, and Alzheimer’s dementia.  However, if you already have prostate cancer, there is a possibility that TRT may accelerate the cancer’s growth and is, therefore, contraindicated.  In women, side effects of acne, unwanted hair growth, or deepening voice, can easily be avoided with proper dosing, frequent lab monitoring, and follow-up visits as is done at the Hammer Institute.